Day 2 :
Keynote Forum
Hana Zelenkova
DOST SvidnÃk, Slovakia
Keynote: The importance of establishing a differential diagnosis in vesicular diseases (HSV infections, dyshidrosis, impetigo)
Time : 10:00-10:45
Biography:
Hana Zelenková has been active in the field of Dermatovenerology since 1973. Since 2000 she has been directing her own Private Clinic of Dermatovenereology. Professional orientation: aesthetic dermatology, acne and facial dermatoses, medicinal mycology (nail diseases), wound management, psoriasis, employment of Ichthyol and carboxytherapy in dermatology. She is a coordinator of many international multicentre trials. More than 555 expert lectures in the Slovak Republic as well as abroad, 440 scientific publications. Co-author of the dermatocosmetic formulae containing Ichthamol and glycyrrhizinic acid. Author of the book “Carboxytherapy” (2015), translated into 4 languages. Regularly invited to deliver lectures at international congresses. Founder and President of the Slovak Society for Aesthetic and Cosmetic Dermatology (SSEDK), organizer and President of the traditional international DERMAPARTY congress. Since 2006 Vice-President European Society of Aesthetic and Cosmetic Dermatology, since 2007 President of the European Society of Aesthetic and Cosmetic Dermatology.
Abstract:
Differential diagnosis is one of the basic pieces of knowledge of every physician, including a dermatologist. Failure in this extraordinarily important area leads to prolongation of problems in an affected patient, their social isolation, higher expenses, or, unfortunately, also to fatal outcomes. It is true that some dermatoses, especially those with vesicular or bullous manifestations, may lead also an experienced dermatologist to erroneous conclusions, which complicates the course of disease and causes even more severe secondary diseases - as shown in the presented case reports. Impetigo and impetiginisation of other dermatoses may be hard to diagnose and treat, especially when the course is bizarre and complicated. This seemingly banal disease must not be underestimated and we must master the bottlenecks of differential diagnostics.
Keynote Forum
Sara M Dann
University of Texas Medical Branch, USA
Keynote: Polymicrobial bacterial infection increases host susceptibility to instestinal inflammation
Time : 11:00-11:45
Biography:
Abstract:
Keynote Forum
Esther Paul
King Khalid University, Saudi Arabia
Keynote: Perspectives of healthcare workers on healthcare-associated infections and infection control in a tertiary care hospital in Abha, Saudi Arabia
Time : 11:45-12:30
Biography:
Abstract:
Keynote Forum
Anil Kaul
Oklahoma State University, USA
Keynote: Trichomonas vaginalis and Chlamydia trachomatis Co-Infections
Biography:
Anil Kaul was graduated from Madras Medical College in Medicine, King Georges’ Medical College in Dentistry and in Public Health from University of Minnesota. He currently serves as the Director of High-Complexity Clinical Laboratories and a Faculty at Oklahoma State University-Center for Health Sciences. He has been awarded 6 patents and has published more than 50 scientific papers. He has served as Senior Health Advisor to the US Department of State and received “Expeditionary Service Award”. In 2014, he also received “Lifetime Achievement Award” at Global Health Summit and in 2008 he was named as Sony’s “Scientist of the Year Award”.
Abstract:
Trichomonas vaginalis (TV) is a common sexually transmitted protozoal infection associated with adverse health outcomes such as preterm birth and symptomatic vaginitis. TV has infected 3.7 million individuals in the United States with new infections expected to increase globally. While wet mount is the least sensitive test for TV, it is still the most common testing method used, despite other methods, including molecular assays being more effective.
Chlamydia trachomatis (CT) is a sexually transmitted disease (STI) with a prevalence of more than 645 cases per 100,000 females in 2015. CT can cause infertility, pelvic inflammatory disease (PID), pregnancy complications, and increased risk of other STIs. Unlike TV, CT is tested through nucleic acid amplification test (NAAT), DNA probe tests, enzyme linked immunosorbent assay (ELISA), and direct florescent antibody test (DFA). By understanding the co-infection rate between TV and CT, better diagnostic protocols can be used for TV diagnosis based on other diagnosis of other common STIs.
Therefore, in this study, we investigated the co-infection rates of CT and TV and collected CT positive patient samples from our clinics. We also collected their de-identified demographic information and performed NAAT based molecular test (Aptima TV assay) using Panther Platform (Hologic Inc. Marlborough, MA) on these patient samples. We determined incidence rate for the overall population and in various demographic sub-groups.
Our results indicate an overall CT/TV co-infection rate of around 22%. The highest co-infection rate was amongst black women in the 18 to 24-year age group. Overall, the co-infection rate in the white population was one-third of the rate in the black population. Because of the high co-infection rates in black women, specifically in the 18-24 age group, interventions are necessary in this demographic group.
Sexual education is critical in preventing future high STI rates. Educating schoolchildren would be ideal, but due to stigma surrounding STIs and sex education, this may not be very effective. Therefore, other methods such as online videos, informational websites, interactive games, social media, and smart phone applications must be explored.
- Multidrug-Resistant Microorganisms
Session Introduction
Raziel Vina S. Espino
East Avenue Medical Center, Philippines
Title: Risk Factors of Multi-Drug Resistant Tuberculosis Among Pediatric Patients: A Retrospective Cohort Study
Biography:
Raziel Vina S. Espino, MD has completed her Doctor of Medicine degree at the age of 23 years from University of the East Ramon Magsaysay Memorial Medical Center in the Philippines. She finished her Pediatric Residency Training at East Avenue Medical Center.
Abstract:
Risk Factors of Multi-Drug Resistant Tuberculosis Among Pediatric Patients: A Retrospective Cohort Study: Determines the risk factors of pediatric patients diagnosed with MDR-TB. Conducted in a tertiary hospital in Quezon City and Health Centers from January 2011 to December 2016. A minimum cohort of 156 patients 0 – 18 years old, either bacteriologically – confirmed or clinically diagnosed tuberculosis were included in the study. Patients whose significant data of their charts went missing were excluded in the analysis. The following information were gathered a.) demographic profile: age, gender, nutritional status, socioeconomic status, district b.) clinical profile, history of exposure, results of laboratories, clinical presentation, delay in treatment, previous treatment with tuberculosis and outcome. 162 patients were analyzed, 12/162 had MDR – TB and 150/162 had Non MDR – TB. Results of univariate analysis showed that age and symptoms of weight loss, back pain, night sweats and fever had significant association with MDR TB. Of these factors, back pain (p=0.001; RR: 31.771; 95% CI: 3.801, 265.554) and fever (p=0.020; RR: 7.6587; 95% CI: 1.380, 42.494) were independent factors significantly related with MDR TB. Age, weight loss, back pain, night sweats and fever had significant association with MDR - TB. Larger sample population and a prospective study is recommended to assess the epidemiologic data and further identify other possible risk factors for resistance.
Vincent TK Chow
University of Singapore, Singapore
Title: The importance of neutrophil extracellular traps and vascular leakage in pneumonia caused by influenza virus and pneumococcus
Time : 12:30-12:55
Biography:
Abstract:
- Healthcare-Associated Infection (HAIs)
Session Introduction
De Nardo E
GOJO Industries, Inc.,
Title: Do Alcohol Based Hand Rubs Have Efficacy Against Multidrug-Resistant Organisms?
Time : 13:55-14:20
Biography:
Elizabeth De Nardo. joined GOJO Industries, Inc. in March 2008 as a Senior Scientist, conducting research projects in collaboration with experts in the areas of infection control, hand hygiene, Norovirus and Microbiome from different US Institutions. She holds a PhD in General Microbiology with expertise in Virology with more than 20 years of experience as a researcher acquired in previous jobs
Abstract:
Background: Multidrug-Resistant Organisms (MRO) including Vancomycin-Resistant Enterococci (VRE), Staphylococcus aureus and the new yeast Candida auris (MDRCA) are often passed from person to person by the contaminated hands of caregivers.
Hands become contaminated by contact with patients infected with MRO or contaminated surfaces. Cleaning hands with soap and water or use alcohol-based hand rubs (ABHR) are the main recommendation of WHO for preventing the spread of MRO in health care settings. However, the efficacy of ABHR against MRO is not well documented Objectives: Determine the efficacy of different formulations of ABHRs (gel and foam) against different strains of MDRO such as VRE, MRSA, Klebsiella and the recent discovered multidrug-resistant yeast Candida auris.
Methods: Three ABHR ranging from 62% to 70% alcohol content in gel and foam format were evaluated using a 15 second in vitro Time-Kill (ASTM E 2315) against several strains of S. aureus. In addition, two formulations of ABHR (gel and foam 70%) were tested against more than 40 strains of antibiotic susceptible and resistant bacteria. For C. auris a different formulation of ABHR was also included. Statistical comparison of log10 reductions (LR) was performed using the Fisher’s LSD Test (p<0.05).
Results: ABHR formulations gel or foam from 62-70% ethanol content, reduced all strains of bacteria antibiotic sensitive or resistant as well as C. auris tested by ≥ 6 log10 (≥ 99.9999%) in 15 seconds.
Conclusions: No differences in susceptibility to alcohol were shown by antibiotic resistant bacteria when compared to the sensitive strains. Alcohol 60% or higher showed the same level of efficacy. The emerging multidrug-resistant yeast Candida auris also showed complete susceptibility to the 3 formulations tested. These results support WHO recommendations for use of ABHR by healthcare personnel for preventing the spread of MRO
Esther Paul
King Khalid University ,School of Medicine, Abha 61421, Kingdom Of Saudi Arabia
Title: Perspectives Of Healthcare Workers On Healthcare -associated Infections And Infection Control In A Tertiary Care Hospital In Abha, Saudi Arabia
Biography:
Dr. Esther Paul has completed her M.B.B.S from the Christian Medical College Ludhiana, Baba Farid University, India and M.D Microbiology from Madras University, India. She has completed her Masters in Public health from the University of Liverpool. Currently she is working as an Assistant professor in the Department of Microbiology King Khalid University, Abha Saudi Arabia. She has published a few papers on Brucella and Burkholderia. She recently presented a paper on Rota virus vaccine at the Vaccine congress, San Diego on September 2017. She is in the process of publishing papers on healthcare associated infections and infection control.
Abstract:
Healthcare workers are in close contact with high-risk inpatients and have the potential to transmit and disseminate healthcare-associated infections. Significant costs, advanced medical care, more extended hospital stay, usage of expensive and stronger antibiotics leading to antibiotic resistance are the adverse consequences of HAIs.The goal of the current study was to understand the perspectives of the healthcare workers on the current protocol and guidelines for HAI and infections control measures in the hospital, the effectiveness of the current protocol for HAI and infection control measures and ways of reducing the incidence of HAI and improve infection control measures.
Methodology: A qualitative research design was used to collect the data from 25 healthcare workers consisting of doctors and nurses, recruited by Snowball strategy via semi-structured interviews which were audio-recorded and transcribed verbatim immediately. An interview guide comprising of open-ended questions about the existing HAI and infection control practices was used to collect the data. Data were analyzed using the thematic analysis method.
Results Using thematic analysis four themes were identified.1.Knowledge of HAI and infection control 2. Infection control measures in practice 3. The gap in infection control measures and HAI 4. Required Implementations.
Conclusion: The study concluded that there is a need for better educational programs and hands-on training for all the healthcare personnel including the paramedical staff as well. The residents should have adequate knowledge of infection control practices to guide the nurses and should share the responsibility with the nurses in the practice of active infection control measures
- Multi Pathogen Infections
Session Introduction
Effah-Acheampong J
School of Public health, University of Ghana, Ghana
Title: Malaria Surveillance System Evaluation, Sunyani Municipality, Ghana-2017
Biography:
Joseph Effah-Acheampong is a public health researcher at a reputable non-governmental organization in Ghana. He holds a BSc in public health and currently pursuing a Master of Philosophy degree in Applied Epidemiology and Diseases Control at the School of Public Health , University of Ghana. With the rudiments in public health he has acquired , he has been involved in a lot of community health with much emphasis on infectious disease and control. He is currently the head of the public health unit of Anidaso Ghana ev. Mr Effah-Acheampong holds a certificate in monitoring and evaluation which gives him the skills to effectively monitor and evaluate interventions which are been implemented at all levels of the disease prevention and control cycle.
Abstract:
Malaria, a preventable mosquito-borne disease, constitutes a major public health problem globally, particularly in Africa where it kills an estimated 394,680 people annually. In Ghana, Malaria accounts for 38.9% of all outpatient illnesses and 38.8% of admissions. Malaria is a priority disease under surveillance. The objective of the study was to evaluate the effectiveness of the surveillance system and assess the attributes and make appropriate recommendations.. We interviewed stakeholders and key informants using semi-structured questionnaires to understand the system operations. We reviewed and compared 2012-2016 malaria registers and reporting forms with existing data in the DHIMS 2. Using SPSS version 21, descriptive data analysis was done. CDC updated guidelines for evaluating public health surveillance system was used in assessing the attributes. Positive malaria cases declined from 50,504 in 2012 to 43,467 in 2013, continual increased to 56540 (47.1%) in 2016. Under 5 positive cases recorded, 2012 recorded 17,852 (35%), 2015 and 2016 recorded17,611(32.8%) and 18,475(32%) respectively. Age group, 1-4 have the highest positive malaria cases, with mean 5,919. Of 88,103 malaria cases treated in 2014, 38.1% (n=33532) were not tested, 13% (n=8739) of 67,295 cases treated were not tested in 2016. Reporting rate of malaria datasets was 97.5%, three (3) out of (30) facilities do not report cases. The system is flexible, sensitive and stable. Timeliness (86%), Completeness (20) and predictive positive value 53,567 (49%) were poor in 2015. The surveillance system is meeting its objectives. Improvement on data completeness and timeliness needs to be done. Suspected malaria should be tested before treatment and followed up. Rigorous supervision on proper documentation and timely reporting should be enforced in the Municipality.
Mojdeh Hakemi Vala
Shahid Beheshti University of Medical Sciences, Iran
Title: Frequency of PmrA, PmrB and mcr-1 genes in pseudomonas aeruginosaisolates from cystic fibrosis patients of mofid children hospital, Tehran, Iran
Biography:
Mojdeh Hakemi Vala is working at Departmentof Microbiology, Medical school, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abstract:
Wang Bowen
Northeast Forestry University, China
Title: Molecular mechanism of low temperature-induced lifespan extension in pine wood nematode(Bursaphelenchus xylophilus)
Biography:
Abstract:
- Infection and Immunity
Session Introduction
Kampong Kamnon
Rajavithi Hospital, Bangkok, Thailand
Title: Effect of Using Collaborative Quality Improvement of Infection Prevention in Tertiary Care Hospital, Bangkok Thailand
Biography:
I am infection control nurse, expertise of infection and prevention control. I am currently work at Rajavithi hospital, Bangkok Thailand. I have experience in supervising, doing the project, consulting and research. Research and presentations include: 2013 Presented research “Effects of using video media on knowledge and health beliefs in prevention of tuberculosis transmission of newly diagnosed pulmonary tuberculosis.” presented “oral presentation of scholarship awardees papers” 13th International congress of the international federation of infection control. Buenos Aires, Argentina. 2016- Presented research “Development of clinical nursing practice guidelines for sepsis patients presented “poster presentation papers” International sepsis forum 2016. Paris, France.
Abstract:
Hospital-associated infections (HAIs) has an impact on patients, personnel and the hospital. This an interrupted time series design study aimed to assess the effect of using collaborative quality improvement (CQI) of infection prevention in tertiary care hospital. The samples were selected by purposive sampling from the patients, who were HAIs and admitted into 6 intensive care units (ICUs) and 36 general wards. Data were collected from May, 2017 to January, 2018. The study instruments were a surveillance form of HAI and impacts of HAI form developed by research. Data were analyzed using descriptive and multiple linear regression statistics. The results revealed that reduction in HAIs, from 35.7 % (1,219/3,417 patients) before implementing CQI to 27.6 % (994/3,608 patients) after implementing CQI at a 0.05 statistically significant levels. Indicated the highest infection rate was from ventilator-associated pneumonia (VAP) 5.6 per 1,000 ventilator-days, followed by catheter-associated urinary tract infection (CAUTI) 3.1 per 1,000 catheter-days and central line-associated bloodstream infection (CLABSI) 1.9 per 1,000 catheter-days. Case fatality rate from VAP, CLABSI and CAUTI were 38.4%, 31.7% and 17.3%. Cost of antibiotic treatment for VAP, CAUTI and CLABSI were 91,153.45 USD, 74,342.72 USD and 20,114.27 USD, respectively. These finding imply that the concept of CQI could be applied to reduce incidence and preventive of HAIs. However, it is interesting to see if the results are sustainable and hospital still proceed with their work.
Beltus Ngulefac
Clinique de l’Ogooue Port-Gentil, Gabon